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Pregabalin 300mg, commonly known under the brand name Lyrica, is a medication primarily used for the treatment of neuropathic pain, fibromyalgia, and generalized anxiety disorder. Each capsule contains 300mg of pregabalin, a chemical compound with the formula C8H17N O2, which modulates the release of certain neurotransmitters, reducing the sensation of pain and anxiety. Pregabaline 300 mg buy online and get control on effective management of neuropathic pain and anxiety.

Mode of action

Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) – an inhibitory neurotransmitter. Researchers suggest that the presynaptic binding of pregabalin to voltage-gated calcium channels plays a key role in its antiseizure and antinociceptive effects.

By binding presynaptically to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system, pregabalin modulates the release of several excitatory neurotransmitters including glutamate, substance-P, norepinephrine, and calcitonin gene related peptide.

Additionally, pregabalin prevents the alpha2-delta subunit from moving from the dorsal root ganglia to the spinal dorsal horn. This action may also contribute to its mechanism of action.

Benefits

• It provides effective relief from neuropathic pain, fibromyalgia, and generalized anxiety disorder.
• It is fast-acting with a quick onset of relief, often within a few hours.
• Most patients tolerate it well, with a lower risk of next-day sedation.
• It is particularly useful for patients who experience chronic pain conditions or anxiety that disrupts their quality of life.
• Furthermore, healthcare providers use pregabalin as adjunctive therapy for treating partial-onset seizures in patients aged 1 month and older.

Side effects of overdose

The overdose of pregabalin can lead to dizziness, drowsiness, confusion, sometimes allergic reactions and respiratory depression. In severe cases, it may result in loss of consciousness or coma. Immediate medical attention is advisable if overdose symptoms are noted.

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